Technician – Protein Production

About Us

Portal Biotech is a pioneering biotechnology company dedicated to developing innovative solutions for proteomics. Our team consists of passionate scientists, engineers, and professionals driven by a shared mission to make a meaningful impact on human health and biology.

About the role:

We are currently seeking a talented and motivated Technician with a background in molecular biology or biochemistry techniques to join our dynamic team. The selected candidate will play a key role in our research and development efforts, contributing to the discovery and development of novel technologies in proteomics and metabolomics. As a technician you will be responsible for conducting protein expression in E. coli, protein purification using different strategies, and molecular cloning. As part of our dynamic research team, you will contribute to the development of multiple projects, gaining hands-on experience in cutting-edge techniques while working in a collaborative and innovative environment.

Responsibilities:

• Perform heterologous protein expression in Escherichia coli using various expression systems.
• Purify proteins using different techniques such as affinity chromatography (His-tag, GST-tag, etc.), ion exchange, size exclusion chromatography (SEC), and other methods.
• Carry out molecular cloning, including PCR, restriction digestion, ligation, and transformation.
• Analyse protein samples using SDS-PAGE, and spectrophotometric assays.
• Maintain accurate and detailed laboratory records in compliance with standard operating procedures (SOP and good laboratory practices (GLP).
• Assist in troubleshooting and optimizing expression and purification protocols.
• Support lab organization, including reagent preparation, equipment maintenance, and inventory management.
• Collaborate with researchers, sharing findings and contributing to project discussions.

Requirements:

• Bachelor’s or Master’s degree in Biochemistry, Molecular Biology, Biotechnology, or a related field.
• Hands-on experience in protein expression and purification.
• Experience with FPLC (ÄKTA system) or other automated purification systems is preferred.
• Familiarity with molecular biology techniques, especially cloning, PCR, and plasmid preparation.
• Strong analytical and problem-solving skills.
• Ability to follow standard protocols and maintain accurate documentation.
• Strong organizational skills and attention to detail.

Benefits:

Portal is an equal opportunities employer. We are enriched by our diversity and are committed to creating and sustaining an inclusive and equitable environment for all. We are a values-led enterprise, and the dedication, passion, and enthusiasm of our talented employees is our cornerstone. We strive to create an environment where our team feel empowered to be their best selves, and where they enjoy working and building both the technologies and our company with us.

Employees receive a competitive salary, 25 days of holiday plus bank holidays, and the opportunity to participate in our share option scheme.

Reach out if you are curious, committed and collaborative, are interested in developing the next generation of biosensing technology.

How to Apply

Scroll down to our applications form below and please submit an updated version of your CV together with your motivation statement and all relevant information to your application.

At Portal Biotech, we believe diversity drives innovation and are committed to fostering an inclusive workplace where all individuals are valued and empowered. We encourage applications from candidates of all backgrounds and experiences.

Join us in our mission to transform healthcare through groundbreaking research and innovation. Apply today!